Biomagnetic Microspheres Solution

Biomagnetic Microspheres Solution

Functional micro nano materials have extensive applications in biomedical fields such as in vitro diagnosis, molecular imaging, and disease treatment due to their rich optical, electrical, magnetic properties, and good biocompatibility. Through years of research and development accumulation and industrial application, we have successfully built three innovative research and development platforms and application solutions around micro and nano material technology.
Functional micro nano materials have extensive applications in biomedical fields such as in vitro diagnosis, molecular imaging, and disease treatment due to their rich optical, electrical, magnetic properties, and good biocompatibility. Through years of research and development accumulation and industrial application, we have successfully built three innovative research and development platforms and application solutions around micro and nano material technology. We will provide high-quality biomedical micro and nano material products, research customization services, and medical product research and development services to our customers.

1.PEG for fluorescence imaging and graphene quantum dots
Graphene quantum dots have great application prospects in biological imaging, and have been confirmed theoretically and experimentally that quantum confinement effects and edge effects can induce graphene quantum dots to emit fluorescence. In the field of biomedical research, fluorescent markers are commonly used to calibrate research objects, but due to excessive excitation time, fluorescence becomes ineffective, which is called photobleaching, which limits the application of general fluorescent agents in biomedical fields. Graphene quantum dots have a stable fluorescent light source, which is also known as "unquenchable fluorescence". By PEG modification, the water solubility, biocompatibility, and in vivo cycling time of graphene quantum dots can be further improved. At the same time, the active targeting ability of PEG fossil graphene quantum dots can be improved by binding targeted molecules.

 
2.Nuclear Medicine Molecular Imaging Probe Carrier - DOTA Modified PEG Nanomaterials
DOTA molecule is a metal element chelating agent with a twelve membered tetraaza macrocyclic ligand. By combining DOTA molecules on the surface of PEG functionalized nanomaterials to chelate radioactive nuclides, nuclear medicine detection is combined with magnetic resonance, optical imaging, and photoacoustic imaging. Targeted molecules and drugs can be incorporated to achieve integrated diagnosis and treatment while achieving multimodal imaging.
   

3.Tumor Targeted Fluorescence/MRI Dual Mode Nanoprobes
Load cy5.5 fluorescent molecules into the bilayer of magnetic lipid nanoparticles to achieve fluorescence/MRI bimodal imaging, and then crosslink cRGD with chemical coupling agents to achieve the goal of targeting tumor neovascularization.

4.Construction of multifunctional liposomes
Diagnosis and targeted therapy are achieved by loading drug peptides and fluorescent molecules inside liposomes and coupling targeted molecules externally.

5.Ultrasonic/Magnetic Resonance Dual Mode Nanoprobes
The microbubble carrier material carrying magnetic nanoparticles, due to its excellent magnetic and acoustic properties, has gradually developed into a multifunctional diagnostic and therapeutic integrated platform that integrates ultrasound/magnetic resonance dual mode imaging, targeted transmission of genes and drugs.

6.Integration of tumor diagnosis and treatment based on magnetic lipid nanoparticles
The tumor targeted imaging nanoprobe based on PEG magnetic nanoparticles combines the functions of magnetic resonance imaging and magnetic induction hyperthermia, and can load lipid soluble fluorescent molecules for fluorescence imaging, as well as combine thermal imaging with magnetic induction of nanoparticles to achieve targeted treatment of tumors under the guidance of multimodal imaging. These studies have shown good advantages and clinical application value in the field of tumor diagnosis and treatment.
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