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2023 Year in Review: Biotechnology Developments

2024-01-15

Assembling an end-of-the-year review is always tricky, especially for biotechnology, a field in which creative energy keeps finding new outlets—and yet somehow multiplies rather than dissipates. A comprehensive review would be exhausting, unless it were to do no more than list significant advances, in which case it would be superficial. A selective review would be more manageable, but it would also risk being arbitrary.

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Organoids Evolve from Academic Marvel to Industrial Tool

2023-12-06

Before the 2023 Society for Laboratory Automation and Screening conference, Corning Life Sciences promised to show its “latest solutions for drug discovery and lab automation with a focus on 3D cell culture.” The company delivered. For example, it presented the Matribot Bioprinter, a semiautomated benchtop system that can dispense and print temperature-sensitive hydrogels without cold blocks, ice buckets, or a cold room. Applications cited by Corning include the printing of pancreatic cancer org

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Roche to Acquire Carmot Therapeutics for Up to $3.1B

2023-12-06

Roche has agreed to acquire Carmot Therapeutics for up to $3.1 billion, the companies said today, in a deal that catapults the buyer into the scramble among biopharmas to develop new obesity drugs.

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NGS Updates from ASHG: What’s New in Sequencing?

2023-11-20

As expected, the NGS companies were sharing their news, out in full force, at the annual American Society for Human Genetics (ASHG) meeting last week in Washington, DC. Whether the updates came from the expo booths showcasing instruments, or users sharing data in the lecture halls, each company had progress to share. Here, we note some of the key highlights we noticed from the meeting.

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New AI Platform Elucidates Regulatory Activity in the Genome

2023-11-20

Researchers investigating the complex gene regulatory mechanisms involved in healthy and disordered biological processes now have a new tool in their kit. Researchers at the University of California, San Diego (UCSD), and elsewhere have developed deep learning software that they claim can be adapted to work for various genomics projects. Details of the software, dubbed genomic elements with neural nets or EUGENe, are provided in Nature Computational Science in a paper titled, “Predictive analysi

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Top 25 Biotech Companies of 2023

2023-11-05

Combined market cap soars 17% over the past year with most of the largest public companies gaining value and biopharma outperforming the S&P 500 year-to-year

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CRISPR Prime Time? FDA Advisory Committee Evaluates Vertex Exa-Cel Therapy for Sickle Cell Disease

2023-11-02

Victoria Gray, a sickle cell patient in the exa-cel trial, makes a cameo appearance at the FDA AdCom meeting. A key FDA Advisory Committee met on Tuesday to discuss Vertex Pharmaceuticals’ groundbreaking IND application of exa-cel, a CRISPR-based therapy for sickle cell disease (SCD).

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Element Biosciences’ NGS Tech, App Stories to Be Featured at ASHG

2023-10-31

Element Biosciences, the developer of the AVITI benchtop sequencer, will be sharing details about its technology and discussing customer stories at the annual meeting of the American Society of Human Genetics (ASHG) annual meeting. Element is a silver sponsor of the meeting, which will be held November 1–5 in Washington, DC.

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