Penn-Century Dry Powder Insufflators™

Introduction

The Injection drug delivery Device series includes liquid pulmonary spray administration device and dry powder insufflator for small animal intratracheal lung delivery. It serves as an alternative tool since Penn-Century retired and closed in 2015. The micro nozzle is integrated into stainless steel capillary cannula. After animal anesthesia, the thin capillary cannula can be inserted deep into the trachea of mice or rats to realize direct pulmonary administration, powered by 2.5ml & 5ml air boosters. Custom configurations for other animal species are available.

Liquid Injection drug delivery Device

Model List

• Injection drug delivery Device for Mouse Cat.No.:BTK-PW-M
• Injection drug delivery Device for Rat Cat.No.:BTK-PW-R
• Injection drug delivery Device for Custom length Cat.No.:BTK-PW-C

1. Main body: transparent glass with graduation marks for liquid quantification. Minimum quantitative unit: 5μL. Optional total volume: 250μL, 500μL, 1mL (250μL by default).
2. Replaceable Tip
   • Tip for Mouse Cat.No.:BJ-PW-M-T
   • Tip for Rat Cat.No.:BJ-PW-R-T
   • Customizable tip length available
3. Optional Quantitative Column: two specifications of 25μL and 50μL for alternative liquid quantification method.
4. Glass spray main body: transparent with scale markings; each graduation represents 5μL.

Dry Powder Injection drug delivery Device (Dry Powder Insufflator)

Model List

• Injection drug delivery Device for Dry Powder (Mouse) Cat.No.:BTK-PW-FM-M
• Injection drug delivery Device for Dry Powder (Rat) Cat.No.:BTK-PW-FM-R
• Injection drug delivery Device for Dry Powder (Custom) Cat.No.:BTK-PW-FM-C

This dry powder insufflator is fitted with disposable 2.5 ml & 5 ml air syringes, silicone rubber valves and hollow stainless steel delivery tube for precise intratracheal dry powder administration. Standard sizes are available for mouse(1.25"), rat (2") or guinea pig(3"), and custom versions for other large animals.

• Function: Fast, precise, targeted delivery of dry powder aerosol cloud into lungs
• Construction: Stainless steel main body + silicone valves; rigid hollow stainless steel delivery tube with rounded tip
• Single dose range: 1–5mg (single-dose loading only). 100mg sample chamber extension accessory available for larger doses
• Air accessory: Compatible with commercial 2.5ml &5ml plastic air syringes (included)
• Powder compatibility: Accepts dry powder ranging from nanoparticles to large macroparticles; the device will not filter or alter powder properties
• Delivery tube dimension (hollow throughout)
  • Mouse: OD 0.7mm, ID 0.4mm
  • Rat: OD 1 mm, ID 0.7mm
• Custom tube options: stainless steel straight / bent tube or flexible plastic tubing; longer tubes can be inserted directly or via endotracheal tube / bronchoscope for larger species
• Sterilization: Detachable stainless steel tip, reusable and autoclavable

Specification Table