Chemical (electrochemical) luminescent magnetic beads
Carboxyl magnetic beads and streptavidin magnetic beads are important raw materials for in vitro diagnostic magnetic bead chemical (electrochemical) luminescence reagents. Magnetic bead chemical (electrochemical) luminescence combines active substances such as antibodies/antigens with active groups on the surface of magnetic beads through streptavidin (SA) labeling or antibody/antigen direct labeling (Figure 1) to coat the magnetic beads. During detection, the test substance and magnetic beads coated with antibodies/antigens, as well as antibodies/antigens labeled with chemical (electrochemical) luminescent molecules, are incubated under certain conditions and bound through antigen-antibody reactions. By increasing the external magnetic field, the magnetic beads generate magnetism and gather together, which can be washed to separate the bound and unbound parts. Finally, the chemical (electrochemical) luminescent molecules are excited, Use a photomultiplier tube to detect signals.
The series of 1-micron and 3-micron scale carboxyl based magnetic beads and SA magnetic beads, composed of polystyrene and nano iron oxide, have excellent size uniformity, superparamagnetism, monodispersity, low serum protein non-specific binding force, slow settling speed, pH, and good temperature stability, and are directly compared to Dynabeads in the United States ® The series of products is the core "core" choice for chemiluminescent magnetic beads.
The series of magnetic beads have been successfully applied in chemiluminescence detection of various clinical indicators, including creatine kinase isoenzyme (CK-MB), N-terminal proBNP precursor (NT proBNP), cardiac troponin T (cTnT), interleukin-6 (IL-6), D-dimer (D-Dimer), total prostate specific antigen (tPSA), free prostate specific antigen (fPSA), cancer antigen 125 (CA125), cytokeratin 19 fragment (CYFRA21-1) Carbohydrate antigen 19-9 (CA19-9), neuron specific enolase (NSE), carcinoembryonic antigen (CEA), pepsinogen I (PGI), pepsinogen ll (PGll), etc. Analyze the repeatability of each kit (10 tests), 37 degree accelerated thermal stability (7 days), and correlation with the standard imported manufacturer's kit, MagBeads ® The series of magnetic beads demonstrate good performance.
Table of the Performance of Magnetic Beads Used in Various Clinical Reagent Kits


Product ordering information
Product Name
|
NO.
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Specifications
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Surface Group
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1 micron hydroxyl magnetic beads
|
BT-MB1001
|
10 mg/uL
|
Hydroxyl
|
1 micron hydroxy magnetic beads (low non-specific)
|
BT-MB1002
|
10 mg/uL
|
Hydroxyl
|
1 micron Streptomyces avidin magnetic beads
|
BT-MB1003
|
10 mg/uL
|
Streptomycin avidin
|
1 micron Streptomyces avidin magnetic beads (low non-specific)
|
BT-MB1004
|
10 mg/uL
|
Streptomycin avidin
|
3-micron hydroxyl magnetic beads
|
BT-MB1005
|
10 mg/uL
|
Hydroxyl
|
3-micron Streptomyces avidin magnetic beads
|
BT-MB1006
|
10 mg/uL
|
Streptomycin avidin
|