Molecular POCT Solution

Molecular POCT Solution

1. Fully automated molecular POCT 2. On machine selection, random access 3. Modularization, independent operation of multiple projects
Molecular POCT products have emerged to overcome the two pain points of complex and polluting conventional PCR operations and long detection times. Firstly, molecular POCT emphasizes "sample in result out" and fully enclosed. This means that after the sample is added, the sample pre-treatment (mainly nucleic acid extraction) and PCR amplification are fully automated in a fully enclosed environment isolated from the surrounding air. This effectively avoids aerosol pollution and sample cross contamination. This can also enable molecular POCT products to theoretically be used outside of PCR laboratories, thereby solving the pain points of strict environmental requirements for nucleic acid testing. In addition, due to the fully automated implementation of the entire nucleic acid detection process in molecular POCT products, the requirements for operators are much lower, and ordinary medical personnel can master it with a little training. This also solves the pain points of requiring professional operators for nucleic acid testing.


Advanced molecular POCT products should have the following characteristics:
1. Advanced sample preparation and reagent stabilization system
The sample preparation adopts an ultrasonic device, and the ultrasonic device of the sample tube can break the original sample and release DNA; The small blue reagent kit body is divided into multiple independent microfluidic sample cells, and different sample cells are connected and closed through the valve rotating device below, thus completing the purpose of washing, purifying, and concentrating DNA. Finally, the concentrated DNA enters the PCR reaction tube and is mixed with the reagent for amplification and detection. This process involves no human contact, minimizing the probability of cross contamination. iPOCT pre packaged reagents use freeze-drying technology, which only requires transportation and storage at room temperature, greatly reducing the requirements for transportation and storage of reagents and greatly facilitating users.

2. Unique fluorescence quantitative PCR system
iPOCT adopts a modular design, with each sample channel having its own independent heating/cooling system, optical signal and detection system. Each module can be independently controlled and operated, and each module can simultaneously perform multiple reaction programs without interfering with each other, making it very suitable for "do as you go", which provides important quality and efficiency assurance for iPOCT.

3. Internal quality control
In terms of operational management and quality control, iPOCT can be described as perfect. It sets up three internal quality control systems: probe detection, internal reference, and sample preparation quality control, ensuring the rigor of the reaction process. Probe detection includes multiple fluorescence detection at different temperatures and comparison of program built-in parameters; The internal reference uses a template similar to the target gene as the internal reference to verify whether each component in the reaction system is working properly; The quality control of sample preparation is different from that of the sample. Different colored fluorescent labeled probes, primers, and samples are used for processing and amplification to control the quality of sample preparation.

4. Full scene application
Nowadays, the focus of the global healthcare industry is not just on having a low-cost central laboratory, but the gap to be filled now is how to find patients. In fact, the unique feature of iPOCT technology lies in its ability to decentralize, allowing testing to be conducted closer to patients without the need to send samples to a central laboratory for testing, greatly reducing turnover, transportation, and waiting times. From the perspective of real-time patients, this is extremely precious.
Our products have always been progressiveness and innovative. They not only provide a test result, but also help doctors optimize the diagnosis and treatment process and improve the treatment effect of patients. In addition to its exquisite and compact product appearance, iPOCT combines its triple attributes of multiple models, modularity, and scalability perfectly, enabling it to meet the needs of users in different scenarios.


5. Multiple models
The iPOCT system is highly integrated and automated, integrating sample preparation and quantitative PCR processes into a closed reagent kit and automatically completing them. Each module is equivalent to a small PCR instrument. The entire process from sample input to result output only takes tens of minutes, which can greatly shorten the time from sample processing to result reporting. At present, there are various models equipped with single channel, 4 channel, 16 channel, etc., which can meet the needs of different users, different usage scenarios, and different speeds, greatly improving detection efficiency and being favored by users. For example, the size of the iPOCT-2000 is only 15 × thirty-five × 33cm, very compact, suitable for various POCT scenarios such as mobile vehicles, on-site emergency response, and clinical portability. The IPOCT instrument can run a rich detection menu and simplify the operator to a professional technician. Regardless of the model chosen, users will receive fast and easy-to-use molecular detection services.
Modularization

6. Modularization
The iPOCT system adopts modular detection, and its dedicated and independent disposable reagent kit is the cornerstone of iPOCT testing. Each module is completely independent and does not affect each other. The testing items that can be carried are related to the number of modules, and can be used to test individual patient samples or wait for batch operation. Therefore, in terms of flexibility, iPOCT is better than many molecular diagnostic automation systems on the market. Users only need to choose the method that best matches their laboratory's workflow or workload through the software.

7. Scalability
The iPOCT system is compact in design, reducing the footprint of the equipment and allowing for installation and operation in almost any situation. And it integrates multiple tests to avoid the hassle of users purchasing multiple different testing platforms. Its scalability is reflected in its stackable design, where users can stack and splice the system like building blocks when the flux demand increases, allowing for rapid expansion. The configuration of different modules can meet different detection flux requirements, with a maximum of 500 detections per day. iPOCT technology has made molecular diagnosis mobile, and any remote and resource scarce area can only have a molecular diagnosis base if it has an iPOCT system.

Molecular POCT is an important branch of laboratory medicine development, and our iPOCT platform integrates fast speed, high throughput, multiple menus, integration, multiple scenarios, and easy operation. It is destined to be the most advanced real-time molecular diagnosis (POCT) platform at home and abroad, playing a leading role in the international and domestic PCR diagnosis market.
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